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The University of Edinburgh

The University of Edinburgh | College of Medicine and Veterinary Medicine |
School of Molecular, Genetic and Population Health Sciences

Centre for Population Health Sciences

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Photo of Sarah Wild

Professor Sarah Wild

Professor of Epidemiology and Honorary Consultant in Public Health, NHS Lothian

Tel: 0131 651 1630
Fax: 0131 650 6868
Sarah.Wild@ed.ac.uk

Role

  • Research in diabetes and cardiovascular disease epidemiology
  • Teaching and supervision of undergraduates, postgraduates and public health trainees
  • Member of M.Sc. course administration team
  • Honorary consultant in public health, Lothian NHS Board
  • Director of Wellcome Trust Clinical Research Facility epidemiology and statistics core

Teaching Responsibilities

Undergraduate
  • Supervision of intercalated B.Sc. students
  • Marker of year 1 Health and Society exams
  • Supervisor of SSC projects
Postgraduate
  • Member of M.Sc. course administration team
  • Course organiser: Introduction to epidemiology
  • Supervision of MD/PhD students
  • Tutor on Sample Size and Evidence Based Medicine workshops

Research Interests

  • Epidemiology of diabetes
  • Epidemiology of cardiovascular disease
  • Routine data linkage
  • Inequalities in health
  • Genetic epidemiology

Current Research Involvement

  • Linkage of national diabetes register data to hospital admission, mortality, cancer registration and other disease register data
  • Viking Health Study - measurement of cardiovascular risk factors and bone mineral density in Shetland
  • Equity audit - examination of equity of selected services in Lothian including coronary revascularisation and breast cancer
  • Telescot research programme - evaluating supported self-monitoring of chronic disease

Other Responsibilities/Activities

  • M.Sc. course team member
  • Honorary consultant in public health, Lothian NHS Board
  • Director of Wellcome Trust Clinical Research Facility Epidemiology and Statistics Core
  • Member of European Diabetes Epidemiology Group steering committee
  • Associate Editor for Diabetologia

Selected grants

  • Validating Existing And Developing New Measures of comorbidity to predict mortality using Scottish routine datasets (Chief Scientist Office, 2013-2015) Wild S, McAllister D, Weir C, Halbesma N
  • The Scottish Health Informatics Programme (SHIP) (Wellcome Trust, 2009-2012) Morris A, Boyle P, Ford I, Bain M, Laurie G, Pagliari C, Cunningham-Burley S, Wild S et al,
  • Telemetric supported self-monitoring of long-term conditions (Chief Scientist Office: NHS Applied Research Programme Grant, 2008-2012) McKinstry B, Pinnock H, MacNee B, Sheikh A, Padfield P, Hanley J, Pagliari C, McKnight J, Wild S, Auld S, Kelly D, Sudlow C.
  • Understanding The Impact Of Diabetes In Scotland: A project to support Scottish diabetes register data linkage. (Scottish Government Health Department, 2008-2010) Wild SH, Lindsay R, Cunningham S, Emslie-Smith A, Fischbacher C, McAlpine R, McGilchrist M, McKnight J, Morris A, Pearson D, Petrie J, Waugh N.
  • Identifying susceptibility loci for osteoporosis by genome wide scan in the UK population isolate of Orkney. (Arthritis Research Council, 2007-2010) Ralston S, Wilson J, Wright A ,Campbell H, Albagha O, Wild S
  • Strategies for optimal reperfusion in ST segment elevation myocardial infarction. A feasibility study for provision of primary percutaneous coronary intervention and pre-hospital thrombolytic therapy in Scotland. (Chief Scientist Office, 2006-2008) Flapan A, Connor P, McLean S, Donald L, Wild S, Craig J
  • A family based intervention for primary prevention of type 2 Diabetes in South Asians: cluster randomised phase iii trial with economic analysis. (National Prevention Research Initiative, 2006-2011) Bhopal R, Sheikh A, Wild S, McKnight J, Wallia S, Lean M, Murray G, Forbes J, Lawton J Further info
  • Risk factors for post-dates pregnancy. (Tenovus, 2005-2006) Denison F, Liston WA, Price J, Wild S, Graham C
  • Statistical methods for describing gene-environment interactions in cardiovascular disease risk factors (Health Services Research studentship). (Chief Scientist Office, 2005-2008) Anderson N, Wild S, Campbell H
  • The impact of deprivation and ethnicity on prevalence of diabetes and its complications: the Glasgow Diabetes Project. (Diabetes UK, 2005-2006) Lindsay R, Wild S, Watt G, Ford I (CI University of Glasgow)
  • Validation of Lothian diabetes register data against routine hospital admission data and examination of potential inequalities by age, sex, deprivation and ethnicity. (Lothian Health Board research and development fund, 2005-2006) Wild S, Carter H
  • Collection of a control cohort from the Scottish population as a national DNA resource for human genetic studies. (Chief Scientist Office Full Grant, 2005-2008) Porteous D, Turner M, Kerr S, Newby D, Wild S
  • National Evaluation of the DHDS Diabetes Screening Pilots. (Department of Health, 2004-2006) Goyder E, Peters J, Lacey A, Wild S, Lawton J, Karnon J, Jiwa M (CI University of Sheffield)
  • Genetic analysis of cardiovascular disease-related traits in Orkney. (Chief Scientist Office, 2004-2007) Wilson J, Campbell H, Wright A, Wild S, Visscher P, Carothers A et al
  • A retrospective cohort study of cardiovascular disease mortality and morbidity among women with endometrial cancer. (Chief Scientist Office, 2004-2004) Wild S
  • Treatment of periodontal disease for glycaemic control in people with diabetes: A Cochrane Systematic Review. (Diabetes UK, 2003-2007) Simpson T, Needleman I, Wild S, Moles D and Mills E

Publications

Link to Edinburgh Research Explorer for up-to-date publications list

Selected publications

  • Bolton JL, Hayward C, Direk N, Lewis JG, Hammond GL, Hill LA, et al (inc Wilson JF, Campbell H, Rudan I, Wild SH, Price JF). Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin. PLoS Genet 2014;10(7):e1004474 DOI Link
  • Genetic Investigation of Anthropometric Traits (GIANT) Consortium (inc J Bolton, H Campbell, G Fowkes, RM Fraser, J Price, I Rudan, SH Wild, JF Wilson). Quality control and conduct of genome-wide association meta-analyses. Nature Protocols 2014;9(5):1192-212 DOI Link
  • Douglas A, Bhopal RS, Bhopal R, Forbes JF, Gill JMR, McKnight J, et al. Design and baseline characteristics of the PODOSA (Prevention of Diabetes & Obesity in South Asians) trial: a cluster, randomised lifestyle intervention in Indian and Pakistani adults with impaired glycaemia at high risk of developing type 2 diabetes. BMJ Open 2013 Jan 1;3(2) DOI Link
  • Bhopal RS, Douglas A, Wallia S, Forbes JF, Lean MEJ, Gill JMR, et al. Effect of a lifestyle intervention on weight change in south Asian individuals in the UK at high risk of type 2 diabetes: a family-cluster randomised controlled trial. The Lancet Diabetes & Endocrinology 2013 Dec 23. DOI Link
  • Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, et al (inc Fraser RM, Bolton JL, Rudan I, Wild SH, Wilson JF, Campbell H, Price JF). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013; published online 6 October DOI Link
  • Global Lipids Genetics Consortium (inc RM Fraser, JL Bolton, I Rudan, SH Wild, JF Wilson, H Campbell, JF Price). Discovery and refinement of loci associated with lipid levels. Nat Genet 2013; published online 6 October DOI Link
  • Morling JR, Balkau B, Wild SH. Diabetes in women - A life-course approach. Menopause International 2013; 19(2):87-95 DOI Link
  • McAllister DA, Morling JR, Fischbacher CM, Macnee W, Wild SH. Socioeconomic deprivation increases the effect of winter on admissions to hospital with COPD: retrospective analysis of 10 years of national hospitalisation data. Prim Care Respir J. 2013; published online 2 July DOI Link
  • Wild S, Hanley J, Lewis S, McKnight J, McCloughan L, Padfield P, Paterson M, Pinnock H, McKinstry B. The impact of supported telemetric monitoring in people with type 2 diabetes: study protocol for a randomised controlled trial. Trials 2013;14:198
  • Stoddart A, Hanley J, Wild S, Pagliari C, Paterson M, Lewis S, Sheikh A, Krishan A, Padfield P, McKinstry B. Telemonitoring-based service redesign for the management of difficult-to-control hypertension (HITS): A cost and cost-effectiveness analysis. BMJ Open 2013;3:e002681
  • McKinstry B, Hanley J, Wild S, Pagliari C, Paterson M, Lewis S, Sheikh A, Krishan A, Stoddart A, Padfield P. Telemonitoring-based service redesign for the management of difficult-to-control hypertension (HITS): a multi-centre randomised controlled trial. BMJ 2013;346:f3030
  • McLean S, Wild SH, Simpson CR, Sheikh A. Models for estimating projections for the prevalence and disease burden of chronic obstructive pulmonary disease (COPD): systematic review protocol. Primary Care Respiratory Journal. 2013;22:PS8-PS21 DOI Link
  • The Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) (inc RM Fraser, JL Bolton, GR Fowkes, SH Wild, I Rudan, H Campbell, JF Wilson, JF Price). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics 2012; published online 12 August DOI Link
  • Wild S, Price J. Epidemiology of type 2 diabetes. Oxford Textbook of Endocrinology and Diabetes 2011, edited by John A H Wass and Paul Stewart; 13.3.3
  • Bhala N, Rosato M, Wild S, Bhopal R, Harding S. Peptic ulcer disease: further work is required to reduce inequalities. Lancet 2010; 375(9714):553
  • Dupuis J et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2009: in press.
  • SDRN Epidemiology Group. Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group. Diabetologia. 2009 Sep;52(9):1755-65
  • McAllister D, Wild S. Why should clinicians understand epidemiology? Postgrad Med J. 2009 Jun;85(1004):313-5.
  • Clough G, Turzyniecka M, Walter L, Krentz A, Wild S, Chipperfield A, Gamble J, Byrne C Muscle Microvascular Dysfunction in Central Obesity is Related to Muscle Insulin Insensitivity but is not Reversed by High-Dose Statin Treatment..Diabetes. 2009 May;58(5):1185-91
  • Bhala N, Bhopal R, Brock A, Griffiths C, Wild S. Alcohol-related and hepatocellular cancer deaths by country of birth in England and Wales: analysis of mortality and census data .J Public Health (Oxf). 2009 Jun;31(2):250-7.
  • Wild SH, Byrne CD, Tzoulaki I, Lee AJ, Rumley A, Lowe GD, Fowkes FG.
  • Hicks AA, Pramstaller PP, Johansson A, Vitart V, Rudan I, Ugocsai P, Aulchenko Y, Franklin CS, Liebisch G, Jonasson I, Pattaro C, Hayward C, Isaacs A, Huffman J, Gnewuch C, Marroni F, Polasek O, Demirkan A, Kolcic I, Schweinbacher C, Igl W, Biloglav Z, Witteman JCM, Pichler I, Zaboli G, Hastie N, Oostra BA, Wild SH, Meitinger T, Gyllensten U, van Duijn CM, Wilson JF, Wright AF, Schmitz G, Campbell H. Genetic determinants of circulating sphingolipid concentrations PLoSGenetics 2009: in press DOI Link
  • Goyder E, Wild S, Fischbacher C, Carlisle J, Peters J. Evaluating the impact of a national pilot screening programme for type 2 diabetes in deprived areas of England. Family Practice 2008;25(5):370-5.
  • McKnight JA, Cline D, Peden N, Fischbacher C, Wild SH. Implementing a National Quality Assurance System for Diabetes Care: The Scottish Diabetes Survey 2001 to 2006 Diabetic Medicine 2008;25(6) 743-6.
  • Denison FC, Price J, Graham C, Wild S, Liston WA. Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term. BJOG. 2008 May;115(6):720-5.
  • Wild S, Byrne CD. Time to rethink high-density lipoprotein? Heart. 2008 Jun;94(6):692-4.
  • Wild S, McLeod F, McKnight J, Watt G, Mackenzie C, Ford I, MacConnachie A, Lindsay RS. Impact Of Deprivation On Cardiovascular Risk Factors In People With Diabetes: An Observational Study Diabet Med. 2008 Feb;25(2):194-9.
  • Wild S, McLeod F, McKnight J, Watt G, Mackenzie C, Ford I, MacConnachie A, Lindsay RS. Impact Of Deprivation On Cardiovascular Risk Factors In People With Diabetes: An Observational Study Diabet Med. 2008 Feb;25(2):194-9.
  • Holt H, Wild SH, Wareham N, Ekelund U, Umpleby M, Shojace-Moradie F, Holt RI, Phillips D, Byrne CD. Differential effects of fatness, fitness and physical activity energy expenditure on whole-body, liver and fat insulin sensitivity.Diabetologia. 2007 Aug;50(8):1698-706.
  • Wild SH, Bryden JR, Lee RJ, Bishop JL, Finlayson A, Byrne CD, Brewster D. Cardiovascular disease, breast cancer and diabetes mortality among women with a history of endometrial cancer. British Journal of Cancer 2007; 96(11):1747-9.
  • Wild SH, Fischbacher CM, Brock A, Griffiths C, Bhopal R. Mortality from all causes and circulatory disease by country of birth in England and Wales 2001-2003. Journal of Public Health 2007 ;29(2):191-8.
  • Wild SH, Forouhi NG. What is the scale of the future diabetes epidemic, and how certain are we about it? Diabetologia. 2007;50(5):903-5.
  • Holt H, Wild SH, Postle AD, Zhang J, Koster G, Umpleby M, Shojace-Moradie F, Dewbury K, Wood PJ, Phillips D, Byrne CD. Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men. Diabetologia 2007 May;50(5):1024-32.
  • Warren RE, Strachan MWJ, Wild SH, McKnight JA. Introducing estimated glomerular filtration rate (eGFR) into clinical practice in the UK: implications for the use of metformin. Diabetic Medicine 2007;24:494-497
  • Wild SH, Byrne CD. Risk factors for diabetes and heart disease. ABC of obesity series no. 7. BMJ 2006; 333:1009-1111
  • Wild SH, Fischbacher CM, Brock A, Griffiths C, Bhopal R. Mortality from all cancers and lung, colorectal, breast and prostate cancer by country of birth in England and Wales, 2001-2003. British Journal of Cancer 2006; 94: 1079-1085.
  • Wild SH, Byrne CD, Smith FB, Lee AJ, Fowkes FGR. Low Ankle-Brachial Pressure Index Increases Risk of Cardiovascular Disease Independently of Metabolic Syndrome and Conventional Cardiovascular Risk Factors In The Edinburgh Artery Study Cohort. Diabetes Care 2006;29(3):637-42.
  • Forouhi NG, Merrick D, Goyder E, Ferguson BA, Abbas J, Lachowycz K, Wild SH. Diabetes prevalence in England, 2001 - estimates from an epidemiological model Diabetic Medicine 2006; 23:189-197.
  • Wild SH, Byrne CD. Treatment of lipids to reduce cardiovascular risk among people with the metabolic syndrome or type 2 diabetes. British Journal of Diabetes and Vascular Disease 2005; 5(6): 315-319.
  • Williams R, Wild S, Shaw J. How many millions have diabetes? Diabetes Voice. 2005; 50(1): 29-32.
  • Wild SH, Byrne CD. The Global Burden of the Metabolic Syndrome and its Consequences for Diabetes and Cardiovascular Disease. Chapter in The Metabolic Syndrome 2005;Wiley Chichester
  • Zhang J, Holt RI, Wild SH, Poole RB, Holt H, Byrne CD. Plasma adiponectin concentrations are independently predicted by fat insulin sensitivity in women and by muscle insulin sensitivity in men. Diabetes Care 2005;28: 755-6
  • Wild SH, Smith FB, Lee AJ, Fowkes FGR. Criteria for previously undiagnosed diabetes and risk of mortality: 15 year follow-up of the Edinburgh Artery Study cohort Diabetic Medicine 2005;22: 490 - 6
  • Wild SH, Byrne CD. The role of treatment to increase HDLc and decrease triglyceride concentrations in prevention of coronary heart disease in type 2 diabetes. Diabetic Medicine 2004; 21(Suppl 4): 8-11.
  • Wild SH, Byrne CD. Evidence for foetal programming of obesity with a focus on putative mechanisms Nutrition Research Reviews 2004: 17: 153-162.
  • Wild SH, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for 2000 and projections for 2030 Diabetes Care 2004;27: 1047-1053
  • Williams DRR, Wild SH. Diabetes prevalence data for the United Kingdom - what do we have and what do we need? Diabetic Medicine 2003; 20: 505-506
  • Gill PS, Kai J, Bhopal RS, Wild SH. Health Needs Assessment for Black and Ethnic Minority Groups (book chapter) Link
  • Wild SH & Byrne CD. Prevention of type 2 diabetes and associated cardiovascular disease . Cardiabetes 2001 1: 20-25.
  • Wild SH & Byrne CD. The benefits of a Mediterranean diet, statins, aspirin and unsaturated fats. Thrombus 2001; 5: 9-11.
  • Wild S, Pierpoint T, McKeigue P, Jacobs H. Long-term consequences of polycystic ovary syndrome: results of a 31 year follow-up study. Hum Fert 2000; 3: 101-105.
  • Wild S, Pierpoint T, McKeigue P, Jacobs H. Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study. Clin Endocrinol (Oxf). 2000; 52: 595-600.
  • Pierpoint T, McKeigue PM, Isaacs AJ, Wild SH, Jacobs HS. Mortality of women with polycystic ovary syndrome at long-term follow-up. J Clin Epidemiol 1998; 723: 581-586.
  • Wild SH, Fortmann SP, Varady AN, Marcovina SP. A case-control study of lipoprotein (a) and myocardial infarction in Stanford Five City Project participants. Arteriosclerosis, Thrombosis and Vascular Biology 1997; 17: 239-245.
  • Wild SH, McKeigue PM. Cross-sectional analysis of mortality by country of birth in England and Wales, 1970-1992. Brit Med J 1997; 314: 705-710.

Last modified: Thursday, 09-Oct-2014 12:32:24 BST

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